Avana 200 mg, which contains Avanafil as its active ingredient, helps in achieving and maintaining an erection primarily by increasing blood flow to the penis during sexual stimulation. Here's how Avana 200 mg works:

Phosphodiesterase Type 5 (PDE5) Inhibition: Avanafil, the active ingredient in Avana 200 mg, belongs to a class of medications known as PDE5 inhibitors. It works by selectively inhibiting the enzyme phosphodiesterase type 5 (PDE5) in the smooth muscle cells of the penis. By inhibiting PDE5, Avana 200 mg promotes the accumulation of cyclic guanosine monophosphate (cGMP) in the smooth muscle cells. This leads to relaxation of the blood vessels and increased blood flow to the erectile tissue of the penis.

Enhanced Blood Flow: Increased blood flow to the penis is crucial for achieving and maintaining an erection. Avana 200 mg facilitates this process by improving the vasodilation (widening) of blood vessels in the penile region. During sexual stimulation, nerve signals trigger the release of nitric oxide (NO) in the erectile tissue. NO then activates an enzyme that produces cGMP, which ultimately relaxes the blood vessels and allows for increased blood flow.

Rapid Onset of Action: Avana 200 mg has a relatively rapid onset of action compared to some other PDE5 inhibitors. It may start working within 15-30 minutes after ingestion, although individual response times can vary. The quick onset of action allows for a more timely response to sexual stimulation, making it easier to achieve an erection when desired.

Duration of Effectiveness: Avanafil, like other PDE5 inhibitors, typically remains effective for 4-6 hours after ingestion. This duration provides a sufficient window of opportunity for sexual activity without the need for frequent dosing. The prolonged effectiveness of Avana 200 mg helps in maintaining an erection throughout the sexual encounter, enhancing sexual satisfaction and performance.